Diondre Overton — a former college football standout at Clemson who helped them win two national championships — has died after an early morning shooting, cops say.

The Guilford County Sheriff’s Office released a statement minutes ago … saying officers responded to a call about a disturbance at around 2:30 AM in Greensboro, North Carolina Saturday.

When they arrived at the scene, they say they found a shooting victim, identified as Overton. Officers administered medical aid, but he was pronounced dead at the scene.

Clemson football’s official X account posted several pictures of the star from his uni days … acknowledging his death and sending condolences to his friends and family.

A number of his teammates posted tributes to their late pal too … including Cincinnati Bengals wide receiver Tee Higgins, who shared a pic to his Instagram story.

On the photo, featuring him and Overton sitting together, Higgins wrote, “Brotha I miss you already man. I love you 5L….I’m hurting bad bout this right now. Rest Easy Big Play.”

Overton played for Clemson from 2016 to 2019 … catching 52 passes for 777 yards and seven TDs over his college career.

He helped Clemson win the National Championship in 2016 and 2018 … and, a plaque outside the stadium bares his name for co-captaining the squad during his senior season.

Overton was 26.