Donald Trump’s crash course in cocaine is taking the internet by storm — mostly ’cause his clueless reactions made it obvious he’s totally lost on the subject!

You absolutely can’t miss the former Prez asking some hard-hitting questions about the topic … wondering if it’s “down and dirty,” or a “stronger up” than booze … awkwardly chuckling with Theo Von on the comedian’s ‘This Past Weekend’ podcast.

The exchange is super laid-back — Theo even straight-up calls Trump his “homie,” and elaborates on the powder he used to take that made him feel like an “owl” — wired and awake all night … what he describes as a miserable feeling. Theo makes it clear he doesn’t do it anymore.

Of course, cocaine’s been showing up in politics headlines lately — it recently emerged because ex-Secret Service Director Kimberly Cheatle wanted to toss the coke found at the White House last year — even after a partial DNA match popped up in a national database.

Her request was shot down because protocol mandates evidence must be kept for 7 years.